I have replaced the didgitiser on an iPad 2 after LCD flex swop out. Digitiser and Home button was all working fine before this. I've tried 2 brand new digitisers now but still the Home button refuses to be responsive. Connectors are fully seated. Now that Jessa has mentioned the signals goes through the charge port I will check that and hope to get this fixed. I haven't changed the port. Will post back when I get a chance to examine it.
Ive got an iPad Air 1 just come in and its giving sll sorts of errors from 14,21, 4014, 4014 and 4005. I've removed LCD and digitiser, downloaded official IPSW's (7.1.2, 9.0 and 9.2) and they all fail at some point. It attempts restore and about 1/3rd of way through what I consider to be the last progress bar it drops out with the error. Oh, Ive also tried different USB ports and cables, all no different. I suspect it to be a hardware fault so I may just remove the logic board and see if that shows anything. Oh great, now iTunes wont even recognise the Air!