My 3DS screen calibration is off

Hello, I own a 3DS and I have noticed for a while that there was minor calibration defects. Since it was minor (a small patch on the touchscreen that didn't respond) I ignored it. I have noticed since then that the stylus also wouldn't match up exactly to the place I tapped, and so it began to be a bit of a problem. I have tried recalibration in the settings but it doesn't seem to be picking up my taps. I really don't want to get another one because there's a program that shut down in future manufactured 3DS's called Flipnote Studio (animation software) and I was lucky enough to get a copy before it got shut down. Please help as soon as you can